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A review on PIM kinases in tumors

31 Jan 2019

Abstract excerpt

The Proviral Integration site for Moloney murine leukemia virus (PIM) kinases is serine/threonine kinases that promote growth and survival in multiple cell types, implicated in the pathogenesis of various diseases. Over expression of Pim-1 experimentally leads to tumor formation in mice, whereas there is no observable phenotype concerning the complete knockout of the protein. When it is over expressed it may lead...

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PMID: 31359998
DOI: 10.6026/97320630015040

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