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Article

Consequences of epidermal growth factor receptor (ErbB1) loss for vascular smooth muscle cells from mice with targeted deletion of ErbB1.

Arteriosclerosis, thrombosis, and vascular biology - 1 Jul 2011

Schreier Barbara, Döhler Maria, Rabe Sindy, Schneider Bettina, Schwerdt Gerald, Ruhs Stefanie, Sibilia Maria, Gotthardt Michael, Gekle Michael, Grossmann Claudia

Abstract excerpt

OBJECTIVE: Pathophysiological effects of the epidermal growth factor receptor (EGFR or ErbB1) include vascular remodeling. EGFR transactivation is proposed to contribute significantly to heterologous signaling and remodeling in vascular smooth muscle cells (VSMC). METHODS AND RESULTS: We investigated the importance of EGFR in primary VSMC from aorta of mice with targeted deletion of the EGFR (EGFR(Δ/Δ...

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Identifiers

PMID: 21512163
DOI: 10.1161/ATVBAHA.111.223537

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EGFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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