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Article

Substance-specific importance of EGFR for vascular smooth muscle cells motility in primary culture.

Biochimica et biophysica acta - 1 Jul 2016

Schreier Barbara, Schwerdt Gerald, Heise Christian, Bethmann Daniel, Rabe Sindy, Mildenberger Sigrid, Gekle Michael

Abstract excerpt

Besides their importance for the vascular tone, vascular smooth muscle cells (VSMC) also contribute to pathophysiological vessel alterations. Various G-protein coupled receptor ligands involved in vascular dysfunction and remodeling can transactivate the epidermal growth factor receptor (EGFR) of VSMC, yet the importance of EGFR transactivation for the VSMC phenotype is incompletely understood. The aims of this...

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Source

Identifiers

PMID: 27012600
DOI: 10.1016/j.bbamcr.2016.03.017

Genes

EGFR
EGF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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