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Article

Role of an intramolecular contact on lipoprotein uptake by the LDL receptor.

Biochimica et biophysica acta - 1 Jun 2011

Zhao Zhenze, Michaely Peter

Abstract excerpt

The LDL receptor (LDLR) is an endocytic receptor that plays a major role in the clearance of atherogenic lipoproteins from the circulation. During the endocytic process, the LDLR first binds lipoprotein at the cell surface and then traffics to endosomes, where the receptor releases bound lipoprotein. Release is acid-dependent and correlates with the formation of an intramolecular contact within the receptor....

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Share to Amino Acid Substitution
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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Lipoproteins, LDL

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Source

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Identifiers

PMID: 21511053
DOI: 10.1016/j.bbalip.2011.04.002
PMCID: PMC3092732

Genes

LDLR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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