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Article

Killing of Kaposi's sarcoma-associated herpesvirus-infected fibroblasts during latent infection by activated natural killer cells.

European journal of immunology - 1 Jul 2011

Matthews Nick C, Goodier Martin R, Robey Rebecca C, Bower Mark, Gotch Frances M

Abstract excerpt

Kaposi's sarcoma-associated herpesvirus (KSHV) establishes life-long infection by evading clearance by the host immune system. In de novo infection and lytic replication, KSHV escapes cytotoxic T cells and NK cells through downregulation of MHC class-I and ICAM-1 molecules and associated antigens involved in forming and sustaining the immunological synapse. However, the efficacy of such mechanisms in the context...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to HLA-E Antigens

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Share to NK Cell Lectin-Like Receptor Subfamily K

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Source

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Identifiers

PMID: 21509779
DOI: 10.1002/eji.201040661
PMCID: PMC3485667

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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