Article
NKp30-dependent cytolysis of filovirus-infected human dendritic cells.
Cellular microbiology - 1 Apr 2007
Fuller Claudette L, Ruthel Gordon, Warfield Kelly L, Swenson Dana L, Bosio Catharine M, Aman M Javad, Bavari Sina
Abstract excerpt
Understanding how protective innate immune responses are generated is crucial to defeating highly lethal emerging pathogens. Accumulating evidence suggests that potent innate immune responses are tightly linked to control of Ebola and Marburg filoviral infections. Here, we report that unlike authentic or inactivated Ebola and Marburg, filovirus-derived virus-like particles directly activated human natural killer...
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