Article
Varicella zoster virus productively infects human natural killer cells and manipulates phenotype.
PLoS pathogens - 1 Apr 2018
Campbell Tessa Mollie, McSharry Brian Patrick, Steain Megan, Ashhurst Thomas Myles, Slobedman Barry, Abendroth Allison
Abstract excerpt
Varicella zoster virus (VZV) is a ubiquitous human alphaherpesvirus, responsible for varicella upon primary infection and herpes zoster following reactivation from latency. To establish lifelong infection, VZV employs strategies to evade and manipulate the immune system to its advantage in disseminating virus. As innate lymphocytes, natural killer (NK) cells are part of the early immune response to infection, and...
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