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Article

Linkage analysis of plasma dopamine β-hydroxylase activity in families of patients with schizophrenia.

Human genetics - 1 Nov 2011

Cubells Joseph F, Sun Xiangqing, Li Wenbiao, Bonsall Robert W, McGrath John A, Avramopoulos Dimitri, Lasseter Virginia K, Wolyniec Paula S, Tang Yi-Lang, Mercer Kristina, Pulver Ann E, Elston Robert C

Abstract excerpt

Dopamine β-hydroxylase (DβH) catalyzes the conversion of dopamine to norepinephrine. DβH enters the plasma after vesicular release from sympathetic neurons and the adrenal medulla. Plasma DβH activity (pDβH) varies widely among individuals, and genetic inheritance regulates that variation. Linkage studies suggested strong linkage of pDβH to ABO on 9q34, and positive evidence for linkage to the complement fixation...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 21509519
DOI: 10.1007/s00439-011-0989-6
PMCID: PMC3193571

Genes

DBH
ABO

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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