Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The Duffy-null state is associated with a survival advantage in leukopenic HIV-infected persons of African ancestry.

Blood - 24 Sept 2009

Kulkarni Hemant, Marconi Vincent C, He Weijing, Landrum Michael L, Okulicz Jason F, Delmar Judith, Kazandjian Dickran, Castiblanco John, Ahuja Seema S, Wright Edwina J, Weiss Robin A, Clark Robert A, Dolan Matthew J, Ahuja Sunil K

Abstract excerpt

Persons of African ancestry, on average, have lower white blood cell (WBC) counts than those of European descent (ethnic leukopenia), but whether this impacts negatively on HIV-1 disease course remains unknown. Here, in a large natural history cohort of HIV-infected subjects, we show that, althou...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Black or African American
Share to Black People

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Duffy Blood-Group System

Share to HIV Infections

Share to Leukocyte Count

Share to Leukopenia

Share to Receptors, Cell Surface

Share to Survival Analysis

Source

Open in PubMed Open full text

Identifiers

PMID: 19620399
DOI: 10.1182/blood-2009-04-215186
PMCID: PMC2927046

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19620399-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The Duffy-null state is associated with a survival advantage in leukopenic HIV-infected persons of African ancestry.PMID 19620399Read ↗

Duffy-null-associated low neutrophil counts influence HIV-1 susceptibility in high-risk South African black women.Semantic proximity Read ↗

Duffy antigen receptor for chemokines mediates trans-infection of HIV-1 from red blood cells to target cells and affects HIV-AIDS susceptibility.Semantic proximity Read ↗

Reduced neutrophil count in people of African descent is due to a regulatory variant in the Duffy antigen receptor for chemokines gene.Semantic proximity Read ↗

Neutrophil counts in persons of African origin.Semantic proximity Read ↗

DARC alleles and Duffy phenotypes in African Americans.Semantic proximity Read ↗

The DARC-null trait is associated with moderate modulation of NK cell profiles and unaltered cytolytic T cell profiles in black South Africans.Semantic proximity Read ↗

Disruption of a GATA motif in the Duffy gene promoter abolishes erythroid gene expression in Duffy-negative individuals.Semantic proximity Read ↗

Relationship between Duffy Genotype/Phenotype and Prevalence of Plasmodium vivax Infestation: A Systematic ReviewSemantic proximity Read ↗

The association between a Darc gene polymorphism and clinical outcomes in African American patients with acute lung injury.Semantic proximity Read ↗

Distribution of Duffy Phenotypes among Plasmodium vivax Infections in SudanSemantic proximity Read ↗

Dynamics and Correlates of CD8 T-Cell Counts in Africans with Primary Human Immunodeficiency Virus Type 1 Infection.Semantic proximity Read ↗

HIV-1 Disease Progression and Survival in an Adult Population in Zimbabwe: Is There an Effect of the Mannose Binding Lectin Deficiency?Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.