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Persistent DNA methylation changes associated with prenatal mercury exposure and cognitive performance during childhood

15 Mar 2017

Abstract excerpt

Prenatal exposure to mercury, a known neurotoxic metal, is associated with lower cognitive performance during childhood. Disruption of fetal epigenetic programming could explain mercury's neurodevelopmental effects. We screened for epigenome-wide methylation differences associated with maternal prenatal blood mercury levels in 321 cord blood DNA samples and examined the persistence of these alterations during...

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PMID: 28325913
DOI: 10.1038/s41598-017-00384-5

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