Article
Geographic differences in allele frequencies of susceptibility SNPs for cardiovascular disease.
BMC medical genetics - 20 Apr 2011
Ding Keyue, Kullo Iftikhar J
Abstract excerpt
BACKGROUND: We hypothesized that the frequencies of risk alleles of SNPs mediating susceptibility to cardiovascular diseases differ among populations of varying geographic origin and that population-specific selection has operated on some of these variants. METHODS: From the database of genome-wide association studies (GWAS), we selected 36 cardiovascular phenotypes including coronary heart disease, hypertension,...
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