Article
Patterns of population differentiation of candidate genes for cardiovascular disease.
BMC genetics - 12 Jul 2007
Kullo Iftikhar J, Ding Keyue
Abstract excerpt
BACKGROUND: The basis for ethnic differences in cardiovascular disease (CVD) susceptibility is not fully understood. We investigated patterns of population differentiation (FST) of a set of genes in etiologic pathways of CVD among 3 ethnic groups: Yoruba in Nigeria (YRI), Utah residents with European ancestry (CEU), and Han Chinese (CHB) + Japanese (JPT). We identified 37 pathways implicated in CVD based on the...
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