Article
Disparities in allele frequencies and population differentiation for 101 disease-associated single nucleotide polymorphisms between Puerto Ricans and non-Hispanic whites.
BMC genetics - 14 Aug 2009
Mattei Josiemer, Parnell Laurence D, Lai Chao-Qiang, Garcia-Bailo Bibiana, Adiconis Xian, Shen Jian, Arnett Donna, Demissie Serkalem, Tucker Katherine L, Ordovas Jose M
Abstract excerpt
BACKGROUND: Variations in gene allele frequencies can contribute to differences in the prevalence of some common complex diseases among populations. Natural selection modulates the balance in allele frequencies across populations. Population differentiation (FST) can evidence environmental select...
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