Lack of association between methylenetetrahydrofolate reductase genetic polymorphisms and postmenopausal breast cancer risk.

doi:10.3892/mmr.2010.406

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Lack of association between methylenetetrahydrofolate reductase genetic polymorphisms and postmenopausal breast cancer risk.

Molecular medicine reports - 1 Jan 2000

Ziva Cerne Jasmina, Stegel Vida, Gersak Ksenija, Novakovic Srdjan

Abstract excerpt

Published data on the association between methylenetetrahydrofolate reductase (MTHFR) gene polymorphisms and breast cancer risk are inconclusive. We investigated the independent and the combined effects of two commonly occurring polymorphisms, MTHFR 677C>T (rs1801133) and MTHFR 1298A>C (rs1801131), as well as their interaction with the use of hormone replacement therapy (HRT), to determine their potential...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Breast

Share to Breast Neoplasms

Share to Case-Control Studies

Share to Hormone Replacement Therapy

Share to Methylenetetrahydrofolate Reductase (NADPH2)

Share to Polymorphism, Genetic

Share to Postmenopause

Share to Risk Factors

Source

Open in PubMed

Identifiers

PMID: 21461582
DOI: 10.3892/mmr.2010.406

Genes

MTHFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Lack of association between methylenetetrahydrofolate reductase genetic polymorphisms and postmenopausal breast cancer risk.PMID 21461582Read ↗

Lack of association between methylenetetrahydrofolate reductase gene A1298C polymorphism and breast cancer susceptibility.Semantic proximity Read ↗

No association between methylenetetrahydrofolate reductase C677T polymorphism and breast cancer.Semantic proximity Read ↗

The common 677C>T gene polymorphism of methylenetetrahydrofolate reductase gene is not associated with breast cancer risk.Semantic proximity Read ↗

Association of 677 C>T (rs1801133) and 1298 A>C (rs1801131) polymorphisms in the MTHFR gene and breast cancer susceptibility: a meta-analysis based on 57 individual studies.Semantic proximity Read ↗

A meta-analysis of genotypes and haplotypes of methylenetetrahydrofolate reductase gene polymorphisms in breast cancer.Semantic proximity Read ↗

Methylenetetrahydrofolate reductase polymorphisms and breast cancer risk: a meta-analysis from 41 studies with 16,480 cases and 22,388 controls.Semantic proximity Read ↗

Folate intake, methylenetetrahydrofolate reductase polymorphisms, and breast cancer risk in women from the Malmö Diet and Cancer cohort.Semantic proximity Read ↗

Methylenetetrahydrofolate reductase and thymidylate synthase polymorphisms are not associated with breast cancer risk or phenotype.Semantic proximity Read ↗

MTHFR 677C>T polymorphism and the risk of breast cancer: evidence from an original study and pooled data for 28031 cases and 31880 controls.Semantic proximity Read ↗

Methylenetetrahydrofolate reductase gene and susceptibility to breast cancer: a meta-analysis.Semantic proximity Read ↗

Association between the MTHFR C677T Polymorphism and Breast Cancer Risk: A Meta-Analysis of 23 Case-Control Studies.Semantic proximity Read ↗

Age at menarche and menopause is not associated with two common genetic variants in the methylenetetrahydrofolate reductase (MTHFR) gene.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.