Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Modeling high-grade serous ovarian carcinogenesis from the fallopian tube

18 Apr 2011

Abstract excerpt

High-grade serous ovarian carcinoma (HGSOC) is a lethal disease for which improved screening and treatment strategies are urgently needed. Progress in these areas is impeded by our poor understanding of HGSOC pathogenesis. Most ovarian cancer research is based on the hypothesis that HGSOC arises from ovarian surface epithelial cells. However, recent studies suggest that >50% of high-grade serous carcinomas...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Ovarian cancer diagnosis and treatment
Share to Reproductive System and Pregnancy
Share to Viral-associated cancers and disorders

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 21502498
DOI: 10.1073/pnas.1017300108

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 23 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Modeling high-grade serous ovarian carcinogenesis from the fallopian tubePMID 21502498Read ↗

Molecular Requirements for Transformation of Fallopian Tube Epithelial Cells into Serous CarcinomaSemantic proximity Read ↗

Cellular models of development of ovarian high‐grade serous carcinoma: A review of cell of origin and mechanisms of carcinogenesisSemantic proximity Read ↗

Both fallopian tube and ovarian surface epithelium are cells-of-origin for high-grade serous ovarian carcinoma.Semantic proximity Read ↗

Both Fallopian Tube and Ovarian Surface Epithelium Can Act as Cell-of-Origin for High Grade Serous Ovarian CarcinomaSemantic proximity Read ↗

In vitro and in vivo correlates of physiological and neoplastic human Fallopian tube stem cellsSemantic proximity Read ↗

Assessing the origin of high-grade serous ovarian cancer using CRISPR-modification of mouse organoids.Semantic proximity Read ↗

Development of Low-Grade Serous Ovarian Carcinoma from Benign Ovarian Serous Cystadenoma CellsSemantic proximity Read ↗

Tumorigenesis and peritoneal colonization from fallopian tube epitheliumSemantic proximity Read ↗

Most Commonly Mutated Genes in High-Grade Serous Ovarian Carcinoma Are Nonessential for Ovarian Surface Epithelial Stem Cell Transformation.Semantic proximity Read ↗

Aged and BRCA-Mutated Stromal Cells Drive Epithelial Cell Transformation.Semantic proximity Read ↗

Rete Ovarii Epithelial Cells as an Unappreciated Cell of Origin for Pelvic and Ovarian High-Grade Serous CarcinomaSemantic proximity Read ↗

Pathogenesis and heterogeneity of ovarian cancerSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.