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Pathogenesis and heterogeneity of ovarian cancer

29 Nov 2016

Abstract excerpt

PURPOSE OF REVIEW: The most common type of ovarian cancer, high-grade serous ovarian carcinoma (HGSOC), was originally thought to develop from the ovarian surface epithelium. However, recent data suggest that the cells that undergo neoplastic transformation and give rise to the majority of HGSOC are from the fallopian tube. This development has impacted both translational research and clinical practice, revealing...

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PMID: 27898521
DOI: 10.1097/gco.0000000000000340

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