Genome-wide association study implicates PARD3B-based AIDS restriction.

doi:10.1093/infdis/jir046

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Article

Genome-wide association study implicates PARD3B-based AIDS restriction.

The Journal of infectious diseases - 15 May 2011

Troyer Jennifer L, Nelson George W, Lautenberger James A, Chinn Leslie, McIntosh Carl, Johnson Randall C, Sezgin Efe, Kessing Bailey, Malasky Michael, Hendrickson Sher L, Li Guan, Pontius Joan, Tang Minzhong, An Ping, Winkler Cheryl A, Limou Sophie, Le Clerc Sigrid, Delaneau Olivier, Zagury Jean-François, Schuitemaker Hanneke, van Manen Daniëlle, Bream Jay H, Gomperts Edward D, Buchbinder Susan, Goedert James J, Kirk Gregory D, O'Brien Stephen J

Abstract excerpt

BACKGROUND: Host genetic variation influences human immunodeficiency virus (HIV) infection and progression to AIDS. Here we used clinically well-characterized subjects from 5 pretreatment HIV/AIDS cohorts for a genome-wide association study to identify gene associations with rate of AIDS progression. METHODS: European American HIV seroconverters (n = 755) were interrogated for single-nucleotide polymorphisms...

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Identifiers

PMID: 21502085
DOI: 10.1093/infdis/jir046
PMCID: PMC3080910

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

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