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Article

Exome sequencing identifies GRIN2A as frequently mutated in melanoma.

Nature genetics - 1 May 2011

Wei Xiaomu, Walia Vijay, Lin Jimmy C, Teer Jamie K, Prickett Todd D, Gartner Jared, Davis Sean, Stemke-Hale Katherine, Davies Michael A, Gershenwald Jeffrey E, Robinson William, Robinson Steven, Rosenberg Steven A, Samuels Yardena

Abstract excerpt

The incidence of melanoma is increasing more than any other cancer, and knowledge of its genetic alterations is limited. To systematically analyze such alterations, we performed whole-exome sequencing of 14 matched normal and metastatic tumor DNAs. Using stringent criteria, we identified 68 genes...

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Identifiers

PMID: 21499247
DOI: 10.1038/ng.810
PMCID: PMC3161250

Genes

TRRAP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-21499247-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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