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Article

Genetic and Functional Analysis of GRIN2A in Tumor Samples.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2017

Prickett Todd D, Gartner Jared J, Samuels Yardena

Abstract excerpt

Ionotropic glutamate receptors (iGluRs) are large integral membrane multi-protein complexes that create ion channels in plasma membranes. Upon binding of receptor specific ligands (e.g., glutamate), increased efflux or influx of mono- or divalent cations (e.g., Ca2+) promotes synaptic transmission, cellular migration, and survival. Three classes of iGluRs were originally defined after their respective agonists:...

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Source

Identifiers

PMID: 28986867
DOI: 10.1007/978-1-4939-7321-7_3

Genes

GRIN1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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