Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mechanism of cargo selection in the cytoplasm to vacuole targeting pathway.

Developmental cell - 1 Dec 2002

Shintani Takahiro, Huang Wei-Pang, Stromhaug Per E, Klionsky Daniel J

Abstract excerpt

The proper functioning of eukaryotic organelles is largely dependent on the specific packaging of cargo proteins within transient delivery vesicles. The cytoplasm to vacuole targeting (Cvt) pathway is an autophagy-related trafficking pathway whose cargo proteins, aminopeptidase I and alpha-mannosidase, are selectively transported from the cytoplasm to the lysosome-like vacuole in yeast. This study elucidates a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Phagosomes
Share to Aminopeptidases
Share to Autophagy-Related Proteins

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Cell Compartmentation

Share to Mannosidases

Share to Transport Vesicles

Share to Vacuoles

Share to Vesicular Transport Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 12479808
DOI: 10.1016/s1534-5807(02)00373-8
PMCID: PMC2737732

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mechanism of cargo selection in the cytoplasm to vacuole targeting pathway.PMID 12479808Read ↗

Cvt19 is a receptor for the cytoplasm-to-vacuole targeting pathway.Semantic proximity Read ↗

Cargo binding to Atg19 unmasks additional Atg8 binding sites to mediate membrane-cargo apposition during selective autophagy.Semantic proximity Read ↗

Membrane protein recycling from the vacuole/lysosome membrane.Semantic proximity Read ↗

Studies of cargo delivery to the vacuole mediated by autophagosomes in Saccharomyces cerevisiae.Semantic proximity Read ↗

Structure of yeast Ape1 and its role in autophagic vesicle formation.Semantic proximity Read ↗

Orchestration of selective autophagy by cargo receptorsSemantic proximity Read ↗

Autophagy, cytoplasm-to-vacuole targeting pathway, and pexophagy in yeast and mammalian cells.Semantic proximity Read ↗

A yeast lysosomal biogenesis map uncovers the cargo spectrum of lysosomal protein targeting pathwaysSemantic proximity Read ↗

Atg27 is required for autophagy-dependent cycling of Atg9.Semantic proximity Read ↗

Mutation at the cargo-receptor binding site of Atg8 also affects its general autophagy regulation function.Semantic proximity Read ↗

Receptor-mediated selective autophagy degrades the endoplasmic reticulum and the nucleus.Semantic proximity Read ↗

The multi-functional SNARE protein Ykt6 in autophagosomal fusion processesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.