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Article

Identifying loci required for follicular patterning using directed mosaics.

Development (Cambridge, England) - 1 Jun 1998

Duffy J B, Harrison D A, Perrimon N

Abstract excerpt

We have developed a 'directed mosaic' system in Drosophila by using the GAL4 system to control the expression of the yeast recombinase, FLP, in a spatial and temporal fashion. By directing FLP expression, we show that it is possible to efficiently and specifically target loss-of-function studies for vital loci to the developmental pathway of interest. A simple F1 adult phenotypic screen demonstrated that most...

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PMID: 9584125
DOI: 10.1242/dev.125.12.2263

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EGF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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