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Article

Mitotic internalization of planar cell polarity proteins preserves tissue polarity.

Nature cell biology - 10 Jul 2011

Devenport Danelle, Oristian Daniel, Heller Evan, Fuchs Elaine

Abstract excerpt

Planar cell polarity (PCP) is the collective polarization of cells along the epithelial plane, a process best understood in the terminally differentiated Drosophila wing. Proliferative tissues such as mammalian skin also show PCP, but the mechanisms that preserve tissue polarity during proliferation are not understood. During mitosis, asymmetrically distributed PCP components risk mislocalization or unequal...

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Identifiers

PMID: 21743464
DOI: 10.1038/ncb2284
PMCID: PMC3149741

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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