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Article

GPCR expression in tissues and cells: Are the optimal receptors being used as drug targets?

14 Apr 2011

Abstract excerpt

G‐protein‐coupled receptors [GPCRs, also known as 7‐transmembrane (7‐TM) receptors] comprise the largest family of membrane receptors in humans and other species and, in addition, represent the greatest number of current drug targets. In this article, we review methods to define GPCR expression and data indicating that individual cells express >100 different GPCRs. Results from studies that have quantified...

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PMID: 21488863
DOI: 10.1111/j.1476-5381.2011.01434.x

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