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Article

5-Azacytidine makes human preadipocytes able to differentiate into mesoderm-derived cell lineages.

Stem cells and development - 1 Jan 2012

Cifarelli Rosa Anna, Conconi Maria Teresa, Marmo Rosa, Di Liddo Rosa, Dininno Caterina, Ferraro Silvia, Cellini Francesco, Parnigotto Pierpaolo

Abstract excerpt

In the present study we have evaluated whether (i) 5-azacytidine (AZA), a well-known demethylating agent, could be able to modify the phenotype of human preadipocytes and (ii) the modified cells could possess multilineage differentiation potential. Human preadipocytes at the 3rd passage were treated for 48 or 96 h with 10 μM AZA and then expanded up to passage 5. Stem cell markers, such as OCT-4, Nanog, and Sox2,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 21488722
DOI: 10.1089/scd.2010.0464

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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