Article

Induction of Muscle Regenerative Multipotent Stem Cells from Human Adipocytes by PDGF-AB and 5-Azacytidine

2020-06-05

Abstract excerpt

<h4>ABSTRACT</h4> Terminally differentiated murine osteocytes and adipocytes can be reprogrammed using platelet-derived growth factor–AB and 5-Azacytidine into multipotent stem cells with stromal cell characteristics. To generate a product that is amenable for therapeutic application, we have modified and optimised culture conditions to reprogram human adipocytes into induced multipotent stem cells (iMS) and expa...

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Literature Corpus work: cc0434cf-8922-59b0-801c-eb37b0b28475
DOI: 10.1101/2020.06.04.130872

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