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The effects of the DNA methyltranfserases inhibitor 5‐Azacitidine on ageing, oxidative stress and DNA methylation of adipose derived stem cells

20 Dec 2016

Abstract excerpt

Human adipose tissue is a great source of adult mesenchymal stem cells (MSCs) which are recognized from their ability to self-renew and differentiation into multiple lineages. MSCs have promised a vast therapeutic potential in treatment many diseases including tissue injury and immune disorders. However, their regenerative potential profoundly depends on patients' age. Age-related deterioration of MSC is...

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Share to Autophagy in Disease and Therapy
Share to Epigenetics and DNA Methylation
Share to Histone Deacetylase Inhibitors Research

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PMID: 27998022
DOI: 10.1111/jcmm.12972

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