Article

Effects of 5-aza-2’-deoxycytidine on human osteoarthritic chondrocytes

2018-11-22

Abstract excerpt

<h4>Background</h4> Given regenerative therapies, the utilization of primary human cells is desired and requested in the development of in vitro systems and disease models. After a few passages in vitro , all cells from the connective tissue end up in a similar fibroblastoid cell type marked by loss of the specific expression pattern. It is still under discussion whether different de-differentiated mesenchymal...

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Literature Corpus work: 96a6393d-0c4b-549f-84fa-987384a642e4
DOI: 10.1101/476069

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