Article
Limited clonal heterogeneity of antigen-specific T cells localizing in the pleural space during mycobacterial infection.
Infection and immunity - 1 Feb 1991
Manca F, Rossi G, Valle M T, Lantero S, Li Pira G, Fenoglio D, De Bruin J, Costantini M, Damiani G, Balbi B
Abstract excerpt
To detect possible differences in phenotype and fine specificity for mycobacterial antigens between CD4-positive T cells from peripheral blood (PB) and from inflammatory sites, we identified four patients presenting with a mycobacterial pleural exudate (PE) rich in PPD-specific lymphocytes and with a negative skin test to tuberculin purified protein derivative (PPD) and a negative proliferative response of PB...
Topics
- Antigens, Bacterial
- Antigens, Differentiation, T-Lymphocyte
- CD4 Antigens
- CD8 Antigens
- Clone Cells
- Humans
- Lymphocyte Activation
- Phenotype
- Pleura
- Skin Tests
- T-Lymphocytes