Evidence for a superantigen in human tuberculosis.

doi:10.1016/1074-7613(94)90007-8

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Article

Evidence for a superantigen in human tuberculosis.

Immunity - 1 Apr 1994

Ohmen J D, Barnes P F, Grisso C L, Bloom B R, Modlin R L

Abstract excerpt

T cells are not only required for resistance to tuberculosis, but they likely contribute to the tissue damage characteristic of the disease. To define better the T cell populations that contribute to the immunopathogenesis of human tuberculosis, we investigated the T cell receptor (TCR) beta chai...

Topics

Amino Acid Sequence
Antigen Presentation
CD4 Antigens
CD8 Antigens
Genetic Variation
Histocompatibility Antigens Class II
Humans
In Vitro Techniques
Lymphocyte Activation
Molecular Sequence Data
Mycobacterium tuberculosis
Polymerase Chain Reaction
Receptors, Antigen, T-Cell, alpha-beta
Superantigens
T-Lymphocyte Subsets
Tuberculin
Tuberculosis, Pleural

Source

Open in PubMed

Identifiers

PMID: 7889397
DOI: 10.1016/1074-7613(94)90007-8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7889397-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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