Article
Evidence for a superantigen in human tuberculosis.
Immunity - 1 Apr 1994
Ohmen J D, Barnes P F, Grisso C L, Bloom B R, Modlin R L
Abstract excerpt
T cells are not only required for resistance to tuberculosis, but they likely contribute to the tissue damage characteristic of the disease. To define better the T cell populations that contribute to the immunopathogenesis of human tuberculosis, we investigated the T cell receptor (TCR) beta chain repertoire expressed in patients with tuberculous pleuritis. Analysis by polymerase chain reaction and flow cytometry...
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