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The application of molecular phylogenetics to the analysis of viral genome diversity and evolution.

Reviews in medical virology - 1 Jan 2000

McCormack Grace P, Clewley Jonathan P

Abstract excerpt

DNA sequencing and molecular phylogenetics are increasingly being used in virology laboratories to study the transmission of viruses. By reconstructing the evolutionary history of viral genomes the behaviour of viral populations can be modelled, and the future of epidemics may be forecast. The manner in which such viral DNA sequences are analysed is the focus of this review. Many researchers resort to the...

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PMID: 12125014
DOI: 10.1002/rmv.355

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