Article
Immunogenetics as a tool in anthropological studies.
Immunology - 1 Jun 2011
Sanchez-Mazas Alicia, Fernandez-Viña Marcelo, Middleton Derek, Hollenbach Jill A, Buhler Stéphane, Di Da, Rajalingam Raja, Dugoujon Jean-Michel, Mack Steven J, Thorsby Erik
Abstract excerpt
The genes coding for the main molecules involved in the human immune system--immunoglobulins, human leucocyte antigen (HLA) molecules and killer-cell immunoglobulin-like receptors (KIR)--exhibit a very high level of polymorphism that reveals remarkable frequency variation in human populations. 'Genetic marker' (GM) allotypes located in the constant domains of IgG antibodies have been studied for over 40 years...
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