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High-Content C. elegans Screen Identifies Natural Compounds Impacting Mitochondria-Lipid Homeostasis and Promoting Healthspan.

Cells - 29 Dec 2021

Maglioni Silvia, Arsalan Nayna, Hamacher Anna, Afshar Shiwa, Schiavi Alfonso, Beller Mathias, Ventura Natascia

Abstract excerpt

The aging process is concurrently shaped by genetic and extrinsic factors. In this work, we screened a small library of natural compounds, many of marine origin, to identify novel possible anti-aging interventions in Caenorhabditis elegans, a powerful model organism for aging studies. To this aim, we exploited a high-content microscopy platform to search for interventions able to induce phenotypes associated with...

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PMID: 35011662
DOI: 10.3390/cells11010100
PMCID: PMC8750055

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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