Article
The Saccharomyces cerevisiae YAK1 gene encodes a protein kinase that is induced by arrest early in the cell cycle.
Molecular and cellular biology - 1 Aug 1991
Garrett S, Menold M M, Broach J R
Abstract excerpt
Null mutations in the gene YAK1, which encodes a protein with sequence homology to known protein kinases, suppress the cell cycle arrest phenotype of mutants lacking the cyclic AMP-dependent protein kinase (A kinase). That is, loss of the YAK1 protein specifically compensates for loss of the A kinase. Here, we show that the protein encoded by YAK1 has protein kinase activity. Yak1 kinase activity is low during...
Topics
- Base Sequence
- Cell Cycle
- Enzyme Induction
- Genes, Fungal
- Genotype
- Intracellular Signaling Peptides and Proteins
- Kinetics
- Molecular Sequence Data
- Oligonucleotide Probes
- Phenotype
- Phosphorylation