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Cryptic Aspergillus nidulans Antimicrobials

9 Apr 2011

Abstract excerpt

Secondary metabolite (SM) production by fungi is hypothesized to provide some fitness attribute for the producing organisms. However, most SM clusters are "silent" when fungi are grown in traditional laboratory settings, and it is difficult to ascertain any function or activity of these SM cluster products. Recently, the creation of a chromatin remodeling mutant in Aspergillus nidulans induced activation of...

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PMID: 21478304
DOI: 10.1128/aem.02000-10

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