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Article

Gene copy number variation throughout the Plasmodium falciparum genome

1 Jan 2009

Abstract excerpt

BACKGROUND: Gene copy number variation (CNV) is responsible for several important phenotypes of the malaria parasite Plasmodium falciparum, including drug resistance, loss of infected erythrocyte cytoadherence and alteration of receptor usage for erythrocyte invasion. Despite the known effects of CNV, little is known about its extent throughout the genome. RESULTS: We performed a whole-genome survey of CNV genes...

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PMID: 19653891
DOI: 10.1186/1471-2164-10-353

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