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Article

Polymorphisms in the E-cadherin (CDH1) gene promoter and the risk of bladder cancer.

European journal of cancer (Oxford, England : 1990) - 1 Dec 2006

Kiemeney Lambertus A, van Houwelingen Kjeld P, Bogaerts Manon, Witjes J Alfred, Swinkels Dorine W, den Heijer Martin, Franke Barbara, Schalken Jack A, Verhaegh Gerald W

Abstract excerpt

AIM: E-cadherin plays a role in carcinogenesis. For two genetic polymorphisms in the gene (CDH1) promoter, a reduced transcription has been reported: a C/A single nucleotide polymorphism (SNP) and a G/GA SNP at -160 bp and -347 bp, respectively, upstream of the transcriptional start site. We studied the association between both polymorphisms and the risk of bladder cancer. METHODS: One hundred and ninety-seven...

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Source

Identifiers

PMID: 16934975
DOI: 10.1016/j.ejca.2006.05.033

Genes

CDH1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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