Article
Genomic selection identifies vertebrate transcription factor Fezf2 binding sites and target genes.
The Journal of biological chemistry - 27 May 2011
Chen Lishan, Zheng Jiashun, Yang Nan, Li Hao, Guo Su
Abstract excerpt
Identification of transcription factor targets is critical to understanding gene regulatory networks. Here, we uncover transcription factor binding sites and target genes employing systematic evolution of ligands by exponential enrichment (SELEX). Instead of selecting randomly synthesized DNA oligonucleotides as in most SELEX studies, we utilized zebrafish genomic DNA to isolate fragments bound by Fezf2, an...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
