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Article

Genes-environment interactions in obesity- and diabetes-associated pancreatic cancer: a GWAS data analysis.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Jan 2014

Tang Hongwei, Wei Peng, Duell Eric J, Risch Harvey A, Olson Sara H, Bueno-de-Mesquita H Bas, Gallinger Steven, Holly Elizabeth A, Petersen Gloria M, Bracci Paige M, McWilliams Robert R, Jenab Mazda, Riboli Elio, Tjønneland Anne, Boutron-Ruault Marie Christine, Kaaks Rudolf, Trichopoulos Dimitrios, Panico Salvatore, Sund Malin, Peeters Petra H M, Khaw Kay-Tee, Amos Christopher I, Li Donghui

Abstract excerpt

BACKGROUND: Obesity and diabetes are potentially alterable risk factors for pancreatic cancer. Genetic factors that modify the associations of obesity and diabetes with pancreatic cancer have previously not been examined at the genome-wide level. METHODS: Using genome-wide association studies (GWAS) genotype and risk factor data from the Pancreatic Cancer Case Control Consortium, we conducted a discovery study of...

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Source

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Identifiers

PMID: 24136929
DOI: 10.1158/1055-9965.EPI-13-0437-T
PMCID: PMC3947145

Genes

GNAS
GNGT2
IMPACT
PTGS1
RELA
TIAM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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