Article
Dynamic redistribution of calcium sensitive potassium channels (hK(Ca)3.1) in migrating cells.
Journal of cellular physiology - 1 Feb 2012
Schwab Albrecht, Nechyporuk-Zloy Volodymyr, Gassner Birgit, Schulz Christoph, Kessler Wolfram, Mally Sabine, Römer Michael, Stock Christian
Abstract excerpt
Calcium-sensitive potassium channels (K(Ca)3.1) are expressed in virtually all migrating cells. Their activity is required for optimal cell migration so that their blockade leads to slowing down. K(Ca)3.1 channels must be inserted into the plasma membrane in order to elicit their physiological function. However, the plasma membrane of migrating cells is subject to rapid recycling by means of endo- and exocytosis....
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