Article
The Ccr4-Not complex interacts with the mRNA export machinery.
PloS one - 28 Mar 2011
Kerr Shana C, Azzouz Nowel, Fuchs Stephen M, Collart Martine A, Strahl Brian D, Corbett Anita H, Laribee R Nicholas
Abstract excerpt
BACKGROUND: The Ccr4-Not complex is a key eukaryotic regulator of gene transcription and cytoplasmic mRNA degradation. Whether this complex also affects aspects of post-transcriptional gene regulation, such as mRNA export, remains largely unexplored. Human Caf1 (hCaf1), a Ccr4-Not complex member, interacts with and regulates the arginine methyltransferase PRMT1, whose targets include RNA binding proteins involved...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
