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Article

[Comparative study of somatic oncogene mutations in normal thyroid tissues and thyroid neoplasms].

Orvosi hetilap - 24 Apr 2011

Tóbiás Bálint, Balla Bernadett, Kósa P János, Horányi János, Takács István, Bölöny Eszter, Halászlaki Csaba, Nagy Zsolt, Speer Gábor, Járay Balázs, Székely Eszter, Istók Roland, Lakatos Péter

Abstract excerpt

It is established that numerous somatic oncogene mutation (BRAF, NRAS, HRAS, KRAS) and gene translocations (RET/PTC, PAX8/PPAR-gamma) are associated with the development of thyroid cancer. In this study 22 intraoperative thyroid tissue samples (11 pathologic and 11 normal) were examined. Somatic single nucleotide polymorphisms were analyzed by LigthCycler melting method, while translocations were identified by...

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Source

Identifiers

PMID: 21464025
DOI: 10.1556/OH.2011.29097

Genes

BRAF
HRAS
NRAS
RET
KRAS
PAX8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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