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Article

Genetic Alterations in Hungarian Patients with Papillary Thyroid Cancer.

Pathology oncology research : POR - 1 Jan 2016

Tobiás Bálint, Halászlaki Csaba, Balla Bernadett, Kósa János P, Árvai Kristóf, Horváth Péter, Takács István, Nagy Zsolt, Horváth Evelin, Horányi János, Járay Balázs, Székely Eszter, Székely Tamás, Győri Gabriella, Putz Zsuzsanna, Dank Magdolna, Valkusz Zsuzsanna, Vasas Béla, Iványi Béla, Lakatos Péter

Abstract excerpt

The incidence of thyroid cancers is increasing worldwide. Some somatic oncogene mutations (BRAF, NRAS, HRAS, KRAS) as well as gene translocations (RET/PTC, PAX8/PPAR-gamma) have been associated with the development of thyroid cancer. In our study, we analyzed these genetic alterations in 394 thyroid tissue samples (197 papillary carcinomas and 197 healthy). The somatic mutations and translocations were detected...

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Source

Identifiers

PMID: 26259532
DOI: 10.1007/s12253-015-9969-9

Genes

RET
BRAF
HRAS
KRAS
NRAS
PAX8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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