No association between methylenetetrahydrofolate reductase C677T polymorphism and breast cancer.

doi:10.1002/cbf.1274

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Article

No association between methylenetetrahydrofolate reductase C677T polymorphism and breast cancer.

Cell biochemistry and function - 1 Jan 2000

Hekim Nezih, Ergen Arzu, Yaylim Ilhan, Yilmaz Hülya, Zeybek Umit, Oztürk Oğuz, Isbir Turgay

Abstract excerpt

Methylenetetrahydrofolate reductase (MTHFR) is an enzyme (EC 1.5.1.20), that reduces 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, a carbon donor for the homocysteine to methionine conversion. MTHFR is a key enzyme that regulates folate metabolism which has an important role in DNA...

Topics

Adult
Breast Neoplasms
Cysteine
Female
Genotype
Humans
Methylenetetrahydrofolate Reductase (NADPH2)
Polymorphism, Genetic
Risk Factors

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