Article
Association of chronic meningococcemia with infection by meningococci with underacylated lipopolysaccharide.
The Journal of infection - 1 Jun 2011
Brouwer Matthijs C, Spanjaard Lodewijk, Prins Jan M, van der Ley Peter, van de Beek Diederik, van der Ende Arie
Abstract excerpt
OBJECTIVES: Chronic meningococcemia is an uncommon manifestation of meningococcal disease. Our objective was to asses whether a bacterial factor, a mutation in the lpxL1 gene resulting in underacylated lipopolysaccharide, might be important in chronic meningococcemia. METHODS: We identified 15 patients with chronic meningococcemia over a 50-year period. Chronic meningococcemia episodes were defined by a febrile...
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