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Article

Identification of genes particularly sensitive to lipopolysaccharide (LPS) in human monocytes induced by wild-type versus LPS-deficient Neisseria meningitidis strains.

Infection and immunity - 1 Jun 2008

Ovstebø Reidun, Olstad Ole Kristoffer, Brusletto Berit, Møller Anne Sophie, Aase Audun, Haug Kari Bente Foss, Brandtzaeg Petter, Kierulf Peter

Abstract excerpt

Lipopolysaccharide (LPS) in the outer membrane of Neisseria meningitidis plays a dominant role as an inflammation-inducing molecule in meningococcal disease. We have used microarray analysis to study the global gene expression after exposure of human monocytes for 3 h to wild-type N. meningitidis (10(6)), LPS-deficient N. meningitidis (10(6) and 10(8)), and purified N. meningitidis LPS (1 ng [33 endotoxin...

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Identifiers

PMID: 18362127
DOI: 10.1128/IAI.01625-07
PMCID: PMC2423066

Genes

CXCL10
CXCL11
CXCL9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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