Article
Genotypic resistance profile of HIV-1 protease gene: a preliminary report from Vellore, south India.
Indian journal of medical microbiology - 1 Jan 2000
Kandathil A J, Kannangai R, Abraham O C, Sudarsanam T D, Pulimood S A, Sridharan G
Abstract excerpt
HIV-1 subtypes other than B are responsible for most new HIV infections worldwide; virus sequence data for drug resistance is described only from a limited number of non-B subtype HIV-1. This study is on mutations and polymorphisms of HIV-1 protease gene that can predict drug resistance in subtype C. The genotypic resistance assay was carried out on 38 HIV-1 strains with their plasma RNA and in nine, the proviral...
Topics
- Amino Acid Substitution
- Drug Resistance, Viral
- Genotype
- HIV Infections
- HIV Protease
- HIV-1
- Humans
- India
- Mutation, Missense
- RNA, Viral
- Sequence Analysis, DNA