Article
HIV type 1 genotypic variation in an antiretroviral treatment-naive population in southern India.
AIDS research and human retroviruses - 1 Apr 2005
Balakrishnan Pachamuthu, Kumarasamy Nagalingeswaran, Kantor Rami, Solomon Suniti, Vidya Sundararajan, Mayer Kenneth H, Newstein Michael, Thyagarajan Sadras P, Katzenstein David, Ramratnam Bharat
Abstract excerpt
Most studies of HIV-1 drug resistance have examined subtype B viruses; fewer data are available from developing countries, where non-B subtypes predominate. We determined the prevalence of mutations at protease and reverse transcriptase drug resistance positions in antiretroviral drug-naive individuals in southern India. The pol region of the genome was amplified from plasma HIV-1 RNA in 50 patients. All...
Topics
- Adult
- Amino Acid Substitution
- Base Sequence
- Drug Resistance, Viral
- Female
- HIV Infections
- HIV Protease
- HIV Reverse Transcriptase
- HIV-1
- Humans