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Article

RS-SNP: a random-set method for genome-wide association studies.

BMC genomics - 30 Mar 2011

D'Addabbo Annarita, Palmieri Orazio, Latiano Anna, Annese Vito, Mukherjee Sayan, Ancona Nicola

Abstract excerpt

BACKGROUND: The typical objective of Genome-wide association (GWA) studies is to identify single-nucleotide polymorphisms (SNPs) and corresponding genes with the strongest evidence of association (the 'most-significant SNPs/genes' approach). Borrowing ideas from micro-array data analysis, we propose a new method, named RS-SNP, for detecting sets of genes enriched in SNPs moderately associated to the phenotype....

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Identifiers

PMID: 21450072
DOI: 10.1186/1471-2164-12-166
PMCID: PMC3079664

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