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Article

Association of variants in the LIPC and ABCA1 genes with intermediate and large drusen and advanced age-related macular degeneration.

Investigative ophthalmology & visual science - 28 Jun 2011

Yu Yi, Reynolds Robyn, Fagerness Jesen, Rosner Bernard, Daly Mark J, Seddon Johanna M

Abstract excerpt

PURPOSE: Intermediate and large drusen usually precede advanced age-related macular degeneration (AMD). There is little information about which genes influence drusen accumulation. Discovery of genetic variants associated with drusen may lead to prevention and treatments of AMD in its early stages. METHODS: A total of 3066 subjects were evaluated on the basis of ocular examinations and fundus photography and...

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Source

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Identifiers

PMID: 21447678
DOI: 10.1167/iovs.10-7070
PMCID: PMC3175969

Genes

ABCA1
LIPC
ARMS2
CFH
HTRA1
APOE
CETP
CFB
CFI

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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