Mycobacterium marinum induces a marked LC3 recruitment to its containing phagosome that depends on a functional ESX-1 secretion system

Abstract excerpt

Autophagy has been implicated as part of the innate immune system against different intracellular microorganisms. Mycobacterium marinum is the causative agent of the fish-tank granuloma and has been widely used as an alternative model to study pathogenic mycobacteria. In this report, we show an active interaction of M. marinum with the autophagic protein LC3, an event that requires pathogen viability and...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Aquaculture disease management and microbiota
• Share to Autophagy in Disease and Therapy
• Share to Vibrio bacteria research studies